業績

2022年 / 2021年 / 2020年 / 2019年 / 2018年 / 2017年 / 2016年 / 2015年 / 2014年 / 2013年 / 2012年 / 2011年 / 2010年 / 2009年 / 2008年 / 2007年 / 2006年 / 2005年 / 2004年 / 2003年 / 2002年 / 2001年

2022年
Original papers

Yamazaki S, Ikeda S, Minami N.
Comparative analysis of histone H3K27me3 modifications between blastocysts and somatic tissues in cattle.
Animal Science Journal, 2022 Jan, 93(1):e13684. doi:10.1111/asj.13684.

Susami K, Ikeda S, Hoshino Y, Honda S, Minami N.
Genome-wide profiling of histone H3K4me3 and H3K27me3 modifications in individual blastocysts by CUT&Tag without a solid support (NON-TiE-UP CUT&Tag)
Scientific Reports, 2022 Jul 11;12(1):11727. doi: 10.1038/s41598-022-15417-x.

Reviews & Books


2021年
Original papers

Ishibashi M, Ikeda S, Minami N.
Comparative analysis of histone H3K4me3 modifications between blastocysts and somatic tissues in cattle.
Scientific Reports, 2021 Apr 15;11(1):8253, doi:10.1038/s41598-021-87683-0.

Reviews & Books
池田俊太郎
体外受精卵産子はなぜ過大子が生まれるのか
家畜診療, 68, 11, 623-628

2020年
Original papers

Shikata D, Yamamoto T, Honda S, Ikeda S, Minami N.
H4K20 monomethylation inhibition causes loss of genomic integrity in mouse preimplantation embryos.
J Reprod Dev, 2020 66(5): 411-419. doi:10.1262/jrd.2020-036.

Miki Y, Devi L, Imai Y, Minami N, Koide T, Goel Sandeep.
Deletion of the PDZ-binding kinase (Pbk) gene does not affect male fertility in mice.
Reprod, Fert Dev, 2020 32(10): 893-902. doi:10.1071/RD19445.

Reviews & Books

2019年
Original papers

Aizawa R, Ibayashi M, Tatsumi T, Yamamoto A, Kokubo T, Miyasaka N, Sato K, Ikeda S, Minami N, Tsukamoto S.
Synthesis and maintenance of lipid droplets are essential for mouse preimplantation embryonic development.
Development, 2019 Nov 25; 146: dev181925 doi: 10.1242/dev.181925.

Goel S, Minami N.
Altered hormonal milieu and dysregulated protein expression can cause spermatogenic arrest in ectopic xenografted immature rat testis.
Scientific Reports, 2019 9(1): 4036. doi: 10.1038/s41598-019-40662-y.

Reviews & Books
池田俊太郎
大学のデスクに座って考えたウシ体外受精卵生産の課題
日本胚移植学雑誌, 2019 41(1): 39-46.

2018年
Original papers

Miki Y, Minami N.
How does the promoter of an oocyte-specific gene function in male germ cells?
J Reprod Dev, 2018 64(6): 463-468. doi: 10.1262/jrd.2018-060.

Honda S, Miki Y, Miyamoto Y, Kawahara Y, Tsukamoto S, Imai H, Minami N.
Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.
J Reprod Dev, 2018 Aug 20; 64(4):297-301. doi: 10.1262/jrd.2018-024. Epub 2018 May 3..

Tatsumi T, Takayama K, Ishii S, Yamamoto A, Hara T, Minami N, Miyasaka N, Kubota T, Matsuura A, Itakura E, Tsukamoto S.
Forced lipophagy reveals that lipid droplets are required for early embryonic development in mouse.
Development, 2018 Feb 23; 145(4). pii: dev161893. doi: 10.1242/dev.161893.

Suyatno, Kitamura Y, Ikeda S, Minami N, Yamada M, Imai H.
Long-term culture of undifferentiated spermatogonia isolated from immature and adult bovine testes.
Mol Reprod Dev., 2018 Mar; 85(3): 236-249. doi: 10.1002/mrd.22958. Epub 2018 Feb 20.

Ikeda S, Sugimoto M, Kume S.
Lipofection of siRNA into bovine 8-16-cell stage embryos using zona removal and the well-of-the-well culture system.
J Reprod Dev., 2018 Apr 13; 64(2): 199-202. doi: 10.1262/jrd.2017-137. Epub 2018 Jan 21.

Ikeda S, Sugimoto M, Kume S.
The RPMI-1640 vitamin mixture promotes bovine blastocyst development in vitro and downregulates gene expression of TXNIP with epigenetic modification of associated histones.
J Dev Orig Health Dis., 2018 Feb; 9(1): 87-94. doi: 10.1017/S2040174417000563. Epub 2017 Aug 2.

Reviews & Books

Suzuki S, Minami N.
CHD1 Controls Cell Lineage Specification Through Zygotic Genome Activation.
Adv Anat Embryol Cell Biol, 2018 229: 15-30. doi: 10.1007/978-3-319-63187-5_3.


鈴木 伸之介・南 直治郎
初期胚の遺伝子発現活性化に関わるエピジェネティック修飾
日本胚移植学雑誌, 2018 40(3): 109-116.

池田俊太郎
栄養素による初期胚のエピジェネティック制御-DOHaDの視点から-
日本胚移植学雑誌, 2018 40(3): 121-131.

2017年
Original papers

Kim N, Minami N, Yamada M, Imai H.
Immobilized pH in culture reveals an optimal condition for somatic cell reprogramming and differentiation of pluripotent stem cells.
Reprod Med Biol, 2017 16(1): 58-66. doi: 10.1002/rmb2.12011.

Nishimura T, Unezaki N, Kanegi R, Wijesekera DPH, Hatoya S, Sugiura K, Kawate N, Tamada H, Imai H. Inaba T.
Generation of Canine Induced Extraembryonic Endoderm-Like Cell Line Forming Embryonic Endoderm Cell Layer.
Stem Cell Dev, 26: **-**, doi: 10.1089/scd.2017.0026.

Nishimura T, Hatoya S, Kanegi R, Wijesekera DPH, Sanno K, Tanaka E, Sugiura K, Kawate N, Tamada H, Imai H. Inaba T.
Feeder-Independent Canine Induced Pluripotent Stem Cells Maintained Under Serum-Free Conditions.
Mol Reprod Dev, 2017 84: 329-339, doi: 10.1002/mrd.22789

Miyamoto K, Tajima Y, Yoshida K, Oikawa M, Azuma R, Allen GE, Tsujikawa T, Tsukaguchi T, Bradshaw CR, Jullien J, Yamagata K, Matsumoto K, Anzai M, Imai H, Gurdon JB, Yamada M.
Reprogramming towards totipotency is greatly facilitated by synergistic effects of small molecules.
Biology Open, 2017 6: 415-424. doi: 10.1242/bio.023473

Ikeda S, Kawahara-Miki R, Iwata H, Sugimoto M, Kume S
Role of methionine adenosyltransferase 2A in bovine preimplantation development and its associated genomic regions.
Scientific Report, 7: 3800, doi: 10.1038/s41598-017-04003-1.

Devi L, Pothana L, Goel S
Dysregulation of angiogenesis-specific signalling in adult testis results in xenograft degeneration.
Scientific Report, 7: 2605, doi: 10.1038/s41598-017-02604-4.

Pothana L, Devi L, Goel S
Cryopreservation of adult cervid testes.
Cryobiology, 2017 74: 103-109. doi: 10.1016/j.cryobiol.2016.11.008

Reviews & Books

林 将文・今井裕
哺乳動物における多能性幹細胞から生殖細胞系列への分化誘導
日本胚移植研究会誌, 2017 39(1):1-7.


2016年
Original papers

Sahare M, Kim SM, Ohtomo A, Komatsu K, Minami N, Yamada M, Imai H.
Factors supporting long-term culture of bovine male germ cells.
Reprod Fert Dev, 2016 28: 2039-2050. doi: 10.1071/RD15003

Kawaguchi T, Cho D, Hayashi M, Tsukiyama T, Kimura K, Matsuyama S, Minami N, Yamada M, Imai H.
Derivation of Induced Trophoblast Cell Lines in Cattle by Doxycycline-Inducible piggyBac Vectors.
PloS One, 2016 Dec 1; 11(12): e0167550. 10.1371/journal.pone.0167550.

Ohta Y, Nagao Y, Minami N, Tsukamoto S, Kito S.
Deficiencies in extrusion of the second polar body due to high calcium concentrations during in vitro fertilization in inbred C3H/He mice.
Zygote, 2016 24(4): 603-616. doi: 10.1017/S096719941500060X.

Pothana L, Devi L, Venna NK, Pentakota N, Varma VP, Jose J and Goel S
Replacement of serum with ocular fluid for cryopreservation of immature testes.
Cryobiology, 2016 73(3): 356-366. doi: 10.1016/j.cryobiol.2016.09.169.

Pothana L, Venna NK, Devi L, Singh A, Chatterjee I and Goel S.
Cryopreservation of adult primate testes.
Europ J Wildlife Res, 2016 62: 619-626. doi: 10.1007/s10344-016-1024-y.

Reviews & Books

Devi L and Goel S.
Fertility preservation through gonadal cryopreservation.
Reprod Med and Biol, 2016 15: 235-251. doi: 10.1007/s12522-016-0240-1.

池田俊太郎
家畜初期胚におけるニュートリエピジェネティクス-One-carbon metabolism の初期胚発生における役割-
栄養生理研究会報, 2016 60(1): 1-11.


2015年
Original papers

Kawaguchi T, Tsukiyama T, Kimura K, Matsuyama S, Minami N, Yamada M, Imai H.
Generation of Naive Bovine Induced Pluripotent Stem Cells Using piggyBac Transposition of Doxycycline-inducible Transcription Factors.
PloS One, 2015 Aug 19; 10(8): e0135403. doi: 10.1371/journal.pone.0135403.

Suzuki S, Nozawa Y, Tsukamoto S, Kaneko T, Manabe I, Imai H, Minami N.
CHD1 acts via the Hmgpi pathway to regulate mouse early embryogenesis.
Development, 2015 Jul 1; 142: 2375-2384; posted ahead of print June 19, 2015, doi: 10.1242/dev.120493.

Suzuki S, Nozawa Y, Tsukamoto S, Kaneko T, Imai H, Minami N.
Histone methyltransferase Smyd3 regulates early embryonic lineage commitment in the mouse.
Reproduction, 2015 Jul 1; 150(1): 21-30. doi: 10.1530/REP-15-0019.

Isaji Y, Yoashida K, Imai H, Yamada M.
An intracytoplasmic injection of deionized bovine serum albumin immediately after somatic cell nuclear transfer enhances full-term development of cloned mouse embryos.
J Reprod Dev, 2015 61(6): 503-510. doi: 10.1262/jrd.2015-031.

Suzuki S, Tsukiyama T, Kaneko T, Imai S, Minami N.
A hyperactive piggyBac transposon system is an easy-to-implement method for introducing foreign genes into mouse preimplantation embryos.
J Reprod Dev, 2015 61(3): 241-244. doi: 10.1262/jrd.2014-157.

Varma VP, Devi L, Venna NK, Murthy CLN, Idris MM and Goel S.
Ocular Fluid as a Replacement for Serum in Cell Cryopreservation Media.
PLoS One, 2015 10(7): e0131291. doi: 10.1371/journal.pone.0131291.

Makala H, Pothana L, Sonam S, Malla and Goel S.
Regeneration of Leydig cells in ectopically autografted adult mouse testes.
Reproduction, 2015 149: 259-268. doi: 0.1530/REP-14-0576.

Pothana L, Makala H, Devi L, Varma V and Goel S.
Germ cell differentiation in cryopreserved immature Indian spotted mouse deer (Moschiola indica) Testes Xenografted onto Mice.
Theriogenology, 2015 83: 625-633. doi: 10.1016/j.theriogenology.2014.10.02.

Devi L, Pawar R, Makala H and Goel S.
Conserved Expression of Ubiquitin Carboxyl-Terminal Esterase L1 (UCHL1) in Mammalian Testes.
Indian J Exp Biol , 2015 53: 305-312.

Kudo M, Ikeda S, Sugimoto M, Kume S.
Methionine-dependent histone methylation at developmentally important gene loci in mouse preimplantation embryos.
J Nutr Biochem, 2015 Dec; 26(12): 1664-9. doi: 10.1016/j.jnutbio.2015.08.009.

Reviews & Books

2014年
Original papers

Tsukamoto S, Hara T, Yamamoto A, Kito S, Minami N, Kubota T, Sato K, Kokubo T.
Fluorescence-based visualization of autophagic activity predicts mouse embryo viability.
Scientific Reports, 2014 Mar 13; 4: 4533. doi: 10.1038/srep04533.

Devi L, Makala H, Pothana L, Nirmalkar K and Goel S.
Comparative efficacies of six different media for cryopreservation of immature buffalo calf (Bubalus bubalis) Testis.
Reprod Fert Dev, 2014 Epub. doi: 10.1071/RD14171.

Kamano S, Ikeda S, Sugimoto M, Kume S.
The effects of calcitonin on the development of and Ca2+ levels in heat-shocked bovine preimplantation embryos in vitro.
J Reprod Dev, 2014; 60(4): 317-23. doi:10.1262/jrd.2013-127

Reviews & Books

2013年
Original papers

Suzuki S, Nozawa Y, Tsukamoto S, Kaneko T, Imai H, Minami N.
ING3 is essential for asymmetric cell division during mouse oocyte maturation.
PLoS One, 2013 Sep 16; 8(9): e74749. doi: 10.1371/journal.pone.0074749.

Ishida M, Okazaki E, Tsukamoto S, Kimura K, Aizawa A, Kito S, Imai H, Minami N.
The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.
PLoS One, 2013 Jul 22; 8(7): e68686. doi: 10.1371/journal.pone.0068686.

Kim SM, Fujihara M, Sahare M, Minami N, Yamada M, Imai H.
Effects of extracellular matrices and the lectin DBA on cell adhesion and self-renewal of bovine gonocytes cultured.
Reprod Fertil Dev, 2013 Feb 21; doi: 10.1071/RD12214.

Tsukamoto S, Hara T, Yamamoto A, Ohta Y, Wada A, Ishida Y, Kito S, Nishikawa T, Minami N, Sato K, Kokubo T.
Functional analysis of lysosomes during mouse preimplantation embryo development.
J Reprod Dev, 2013 Feb 20; 59: 33-39. doi: 10.1262/jrd.2012-096.

Isaji Y, Murata M, Takaguchi N, Mukai T, Tajima Y, Imai H, Yamada M.
Valproic acid treatment from the 4-cell stage improves Oct4 expression and nuclear distribution of histone H3K27me3 in mouse cloned blastocysts.
J Reprod Dev, 2013 59: 196-204. doi: 10.1262/jrd.2012-156.

Reddy N, Sreshtha S, Katakam M, Ashwini M, Sonam S, Kumar V and Goel S.
Prepubertal buffalo (bubalus bubalis) leydig cells: isolation, culture and characterization.
J Buffalo Sci, 2013 2:23-33.

Kuroki T, Ikeda S, Okada T, Maoka T, Kitamura A, Sugimoto M, Kume S.
Astaxanthin ameliorates heat stress-induced impairment of blastocyst development in vitro:--astaxanthin colocalization with and action on mitochondria--.
J Assist Reprod Genet, 2013 30: 623-31. doi: 10.1007/s10815-013-9987-z.

Reviews & Books

Ikeda S., Yamada M.
Midkine and cytoplasmic maturation of mammalian oocytes in the context of ovarian follicle physiology.
Br J Pharmacol Review, doi: 10.1111/bph.12311., 2013


2012年
Original papers

Yamamizu K, Fujihara M, Tachibana M, Katayama S, Takahashi A, Hara E, Imai H, Shinkai Y, and Yamashita JK.
Protein Kinase A Determines Timing of Early Differentiation through Epigenetic Regulation with G9a.
Cell Stem Cell, 10(6):759-70 (2012)

浅野良太、川口高正、今井 裕
哺乳動物におけるiPS細胞
日本胚移植学雑誌、34巻、1号、9-18 (2012)

伊佐治優希、村田萌子、田島陽介、今井裕、山田雅保
ノコダゾール処理除核卵母細胞由来マウス体細胞核移植胚の発生に及ぼすスクリプタイドの効果
日本胚移植学雑誌、34巻、117-127 (2012)

Ikeda S, Sugimoto M, Kume S.
Importance of methionine metabolism in morula-to-blastocyst transition in bovine preimplantation embryos.
J Reprod Dev, 2012; 58(1): 91-7. doi.org/10.1262/jrd.11-096H.

Reviews & Books

Yamada M, Isaji Y, Ikeda S.
Midkine, a Factor Promoting Cytoplasmic Maturation of Oocytes.
Midkine: From Embryogenesis to Pathogenesis and Therapy. (Eds; Erguven, et al.) Dordrecht: Springer, P183-193 (2012)

Ikeda S, Koyama H, Sugimoto M, Kume S.
Roles of one-carbon metabolism in preimplantation period--effects on short-term development and long-term programming--.
J Reprod Dev, 2012; 58(1): 38-43. doi.org/10.1262/jrd.2011-002.


2011年
Original papers

Fujihara M, Kim SM, Minami N, Yamada M and Imai H.
Characterization and in vitro culture of male germ cells from developing bovine testis.
J Reprod Dev, 2012 Oct 19; 59: 33-39.

Tsukiyama T, Asano R, Kawaguchi T, Kim N, Yamada M, Minami N, Ohinata Y, Imai H.
Simple and efficient method for generation of induced pluripotent stem cells using piggyBac transposition of doxycycline-inducible factors and an EOS reporter system.
Genes to Cells, 16(7): 815-825. (2011)

星野洋一郎、南 直治郎、今井 裕
無線ICタグを用いた凍結精液流通管理システムの開発と実証試験
日本胚移植研究会誌、33巻、1号、33-41 (2011)

Horii T, Suetake I, Yanagisawa E, Morita S, Kimura S, Nagao Y, Imai H, Tajima S, Hatada I.
The Dnmt3b Splice Variant is Specifically Expressed in In Vitro-manipulated Blastocysts and Their Derivative ES Cells.
J Reprod Dev, 57 (5): 579-585 (2011)

Goel S, Mahla RS, Suman SK, Reddy N and Imai H.
UCHL-1 protein expression specifically marks spermatogonia in wild bovid testis.
Eur J Wild Res, 57: 663-667. (2011)

Miyamoto K, Nagai K, Kitamura N, Nishikawa T, Ikegami H, Binh NT, Tsukamoto S, Matsumoto M, Tsukiyama T, Minami N, Yamada M, Ariga H, Miyake M, Kawarasaki T, Matsumoto K, Imai H.
Identification and characterization of an oocyte factor required for development of porcine nuclear transfer embryos.
Proc Natl Acd Sci USA, 108 (17): 7040-7045, (2011)

北村 尚也、松本 舞、今井 裕
無細胞抽出系を用いた体細胞に対するリプログラミング誘導
日本胚移植研究会誌、33巻、1号、1-7(2011)

Reviews & Books

Goel S and Imai H.
Pluripotent stem cells from testis, in "Embryonic Stem Cells - Differentiationand Pluripotent Alternatives"(Chapter 24)

ed. Michael S. Kallos, InTech Publisher, Rijeka, pp. 473-492. (2011) ISBN 978-953-307-632-4

Yamada M., Isaji Y.
Structural and functional changes linked to, and factors promoting, cytoplasmic maturation in mammalian oocytes.
Reprod Med Biol 10: 69-79. (2011) Review

南 直治郎
卵母細胞特異的に発現するOog1について
「卵子学」(森 崇英 総編集)pp. 803-805. (2011) 京都大学学術出版会 ISBN 978-4-87698-924-9

山田雅保
卵母細胞の細胞質成熟
「卵子学」(森 崇英 総編集)pp. 329-337. (2011) 京都大学学術出版会 ISBN 978-4-87698-924-9

山田雅保
卵子成熟と遺伝子発現
Hormone Frontier in Gynecology Vol. 18, 27-31 (2011)


2010年
Original papers

Kioka N, Ito T, Yamashita H, Uekawa N, Umemoto T, Motoyoshi S, Imai H, Takahashi K, Watanabe H, Yamada M, Ueda K.
Crucial role of vinexin for keratinocyte migration in vitro and epidermal wound healing in vivo.
Exp Cell Res, 316 (10): 1728-1738. (2010)

Goel S, Reddy N, Mandal S, Fujihara M, Kim S-M, Imai H.
Spermatogonia-specific proteins expressed in prepubertal buffalo (Bubalus bubalis) testis and their utilization for isolation and in vitro cultivation of spermatogonia.
Theriogenology, 74 (7): 1221-1232. (2010)

Ikeda S, Namekawa T, Sugimoto M, Kume S.
Expression of methylation pathway enzymes in bovine oocytes and preimplantation embryos.
J Exp Zool A Ecol Genet Physiol, 313(3):129-36. doi: 10.1002/jez.581. (2010)


2009年
Original papers

Goel, S, Fujihara M, Tsuchiya K, Takagi Y, Minami N, Yamada M, Imai H.
Multipotential ability of primitive germ cells from neonatal pig testis cultured in vitro.
Reprod Fertil Dev, 21: 696-708 (2009)

Miyamoto K, Tsukiyama T, Yang Y, Ning L, Minami N, Yamada M, Imai H.
Cell-Free Extracts from Mammalian Oocytes Partially Induce Nuclear Reprogramming in Somatic Cells.
Biol Reprod, 80: 935-943 (2009)


2008年
Original papers

Miyamoto K, Yamashita T, Tsukiyama T, Kitamura N, Minami N, Yamada M, Imai H.
Reversible Membrane Permeabilization of Mammalian Cells Treated with Digitonin and Its Use for Inducing Nuclear Reprogramming by Xenopus Egg Extracts.
Cloning and Stem Cells, 10: 535-542, 2008

Fujihara M, Goel S, Minami N, Yamada M, Imai H.
Cryopreservation in liquid nitrogen of gonocytes from neonatal porcine testes stored at 4℃.
Reprod Med Biol, 7: 153-160, 2008

Goel S, Fujihara M, Minami N, Yamada M, Imai H.
Expression of NANOG, but not POU5F1, points to the stem cell potential of primitive germ cells in neonatal pig testis.
Reproduction, 135: 785-795, 2008.

Reviews & Books

Watanabe T, Imai H, Minami N.
Identification and Expression Analysis of Small RNAs During Development
Methods Mol Biol, 442: 173-185, 2008.

宮本圭、今井裕
卵細胞抽出液を用いた体細胞のリプログラミング誘導
幹細胞の分化誘導と応用 印刷中 エヌ・ティー・エス出版 2008.

大石理恵子、今井裕、山田雅保
総説:卵母細胞の成熟に関する最近の知見
日本胚移植学雑誌、30:87-98、2008.

山田雅保
動物の初期発生I その形態的特徴、マウスの初期発生
「発生生物学」 (村井耕二 編集)、pp.69-72. (2008) 化学同人

山田雅保
動物の器官形成II,四肢と生殖腺の形成
「発生生物学」 (村井耕二 編集)、pp.109-119. (2008) 化学同人

山田雅保・酒井則良

動物の配偶子形成と受精
「発生生物学」 (村井耕二 編集)、pp.121-133. (2008) 化学同人

山田雅保
動物と植物 発生原理の共通性と特殊性 全能性とクローン生物
「発生生物学」 (村井耕二 編集)、pp.164-166. (2008) 化学同人


2007年
Original papers

Miyamoto K, Furusawa T, Ohnuki M, Goel S, Tokunaga T, Minami N, Yamada M, Ohsumi K, Imai H.
Reprogramming events of mammalian somatic cells induced by Xenopus laevis egg extracts.
Mol Reprod Dev, 74: 1268-1277, 2007.

Suzuki T, Kono T, Minami N, Imai H.
Comparison of RNA polymerase I-, II- and III-dependent transcripts levels between nuclear transfer and in vitro fertilized embryos at the blastocyst stage
J Reprod Dev, 53: 663-671, 2007.

Goel S, Sugimoto M, Minami N, Yamada M, Kume S, Imai H.
Identification, Isolation, and In Vitro Culture of Porcine Gonocytes.
Biol Reprod, 77: 127-137, 2007.

Ji M, Minami N, Yamada M, Imai H.
Effect of protopanaxatriol saponin in spermatogenic stem cell survival in busulfan-treated male mice.
Reprod Med Biol, 6: 99-108, 2007.

Cao L, Shitara H, Horii T, Nagao Y, Imai H, Abe K, Hara T, Hayashi J, Yonekawa H.
The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells.
Nature Genetics, 39: 386-390, 2007.

Miyamoto K, Hoshino Y, Minami N, Yamada M, Imai H.
Effects of Synchronization of Donor Cell Cycle on Embryonic Development and DNA Synthesis in Porcine Nuclear Transfer Embryos
J Reprod Dev, 53: 237-246, 2007.

Reviews & Books

Minami N, Suzuki T, Tsukamoto S.
Zygotic gene activation and maternal factors in mammals.
J Reprod Dev, 53: 707-715, 2007.

Watanabe T, Totoki Y, Sasaki H, Minami N, Imai H.
Analysis of small RNA profiles during development.
Methods Enzymol, 427: 155-169, 2007.


2006年
Original papers

Suzuki T, Minami N, Kono T, Imai H.
Zygotically Activated Genes Are Suppressed in Mouse Nuclear Transferred Embryos.
Cloning and Stem Cells, 8: 295-304, 2006.

Ikeda S, Saeki K, Imai H, Yamada M.
Abilities of cumulus and granulosa cells to enhance the developmental competence of bovine oocytes during in vitro maturation period are promoted by midkine; a possible implication of its apoptosis suppressing effects.
Reproduction, 132: 549-557, 2006.

Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H.
Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
Genes and Development, 20: 1732-1743, 2006.

Tsukamoto S, Ihara R, Aizawa A, Kishida S, Kikuchi A, Imai H, Minami N.
Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.
Biochem Biophys Res Commun, 343: 1105-1112, 2006.

Reviews & Books

Minami N and Tsukamoto S.
Role of oocyte-specific genes in the development of mammalian embryos
Reprod Med Biol, 5: 175-182, 2006.


2005年
Original papers

Hoshino Y, Uchida M, Shimatsu Y, Miyake M, Nagao Y, Minami N, Yamada M, Imai H.
Developmental competence of somatic cell nuclear taransfer embryos reconstructed from oocytes matured in vitro with follicle shells in minature pig.
Cloning and Stem Cells, 7: 17-26, 2005.

Dateki M, Horii T, Kasuya Y, Mochizuki R, Nagao Y, Ishida J, Sugiyama F, Tanimoto K, Yagami K, Imai H, Fukamizu A.
Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in epileptic seizure.
J Biol Chem, 280: 20503-20508, 2005.

Watanabe T, Takeda A, Mise K, Okuno T, Suzuki T, Minami N, Imai H.
Stage-specific expression of microRNAs during Xenopus development.
FEBS Lett, 579: 318-324, 2005.

Reviews & Books

Ikeda S, Kitagawa M, Imai H, Yamada M.
The roles of vitamin A for cytoplasmic maturation of bovine oocytes.
J Reprod Dev, 51: 23-35, 2005.


2004年
Original papers

Shimatsu Y., Uchida M., Niki R. and Imai H.
Effects of a synthetic progestogen, altrenogest, on oestrus synchronisation and fertility in miniature pigs.
Veterinary Record., 155: 633-635, 2004.

Reviews & Books

南直治郎、朴志秀
ウシ体細胞クローン胚における遺伝子発現パターンの解析
畜産技術 6月号 p.2-5. 畜産技術協会 2004.

今井裕
バイオテクノロジーのための基礎分子生物学、大嶋泰治、北本勝彦、原島俊、宮川都吉(編)
トランスジェニック動物、p. 181-183、化学同人、京都、2004.

今井裕
学問紙風船―発生工学・生殖工学―(監修)
Guideline 11, 56-57、河合塾、2004.

山田雅保
初期発生の遺伝子コントロール -ほ乳類の着床前期胚の発生- p. 1-104
朝倉書店、東京、2004

山田雅保
家畜の発生工学
京大人気講義シリーズ バイオサイエンスの新戦略(京都大学農学部 編)、p88-101、丸善株式会社、東京、2004


2003年
Original papers

Ikeda S., Imai H. and Yamada M.
Apoptosis in cumulus cells during in vitro maturation of bovine cumulus-enclosed oocytes.
Reproduction, 125: 369-376, 2003.

Horii T., Nagao Y., Tokunaga T. and Imai H.
Serum-free culture of murine primordial germ cells and embryonic germ cells.
Theriogenology, 59: 1257-1264, 2003.

Takeda K., Akagi S., Kaneyama K., Kojima T., Takahashi S., Imai H., Yamanaka M., Onishi A. and Hanada H.
Proliferation of donor mitochondrial DNA in nuclear transfer calves (Bos taurus) derived from cumulus cells.
Mol. Reprod. Dev., 64: 429-437, 2003.

Totsuka Y., Nagao Y., Horii T., Yonekawa H., Imai H., Hatta H., Izaike Y., Tokunaga T. and Atomi Y.
Physical performance and soleus muscle fiber composition in wild-derived and laboratory inbred mouse strains.
J. Appl. Physiol., 95: 720-727, 2003.

Minami N., Aizawa A., Ihara R., Miyamoto M., Ohashi A. and Imai H.
Oogenesin is a novel mouse protein expressed in oocytes and early cleavage stage embryos.
Biol. Reprod., 69: 1736-1742, 2003.

Ohashi A., Imai H. and Minami N.
Cyclin A2 is phosphorylated during the G2/M transition in mouse 2-cell embryos.
Mol. Reprod. Dev., 66: 343-348, 2003.

Kigami D., Minami N., Takayama H. and Imai H.
MuERV-L is one of the earliest transcribed genes in mouse one-cell embryos.
Biol. Reprod., 68: 651-654, 2003.

Reviews & Books

今井裕
クローン技術の現状と将来
高圧ガス、40巻、1号、25-27、2003

今井裕
分子生物学・免疫学キーワード辞典
永田和宏、宮坂昌之、宮坂信之、山本一彦(編)、医学書院、東京、2003

今井裕・大澤勝次
健康と食を問い直す生物学―食の未来を考える
岩波書店、東京、2003

今井裕
体細胞からの個体形成―クローン技術―
サイエンティスト、第3号、2-14、奈良、2003

山田雅保
家畜の繁殖
資源生物科学概論(京都大学農学部資源生物科学編)、ショウワドウ・イープレス株式会社、京都、2003


2002年
Original papers

Iwata H., Kimura K., Hashimoto S., Ohta M., Tominaga T. and Minami N.
Role of G6PD activity on sex ration and developmental competence under oxidative stress.
J. Reprod. Dev., 48: 447-453, 2002.

Takeda K., Hasegawa K., Ichino K., Imai A., Kanayama K., Takahashi S., Akagi S., Imai H., Yamanaka M., Ohnishi A., Hanada H.
Mitochondrial type in bovine nuclear transfer off-spring: Factors which cause heteroplasmy.
Japanese Journal of Embryo Transfer, 24; 13-18, 2002.

Hashimoto S., Minami N., Takakura R. and Imai H.
Bovine Immature Oocytes Acquire Developmental Competence during Meiotic Arrest in vitro.
Biol. Reprod., 66; 1696-1701, 2002.

Kurosaka S., Nagao Y., Minami N., Yamada M. and Imai H.
Dependence of DNA synthesis and in vitro development of bovine nuclear transfer embryos on the stage of the cell cycle of donor cells and recipient cytoplast.
Biol. Reprod., 67; 643-647, 2002.

Matsukawa T., Ikeda S., Imai H. and Yamada M.
Alleviation of the two-cell block of ICR mouse embryos by polyaminocarboxylate metal chelators.
Reproduction, 124; 65-71, 2002.

Azuma T., Kondo T., Ikeda S., Imai H. and Yamada M.
Effects of EDTA saturated with Ca2+(Ca-EDTA) on pig, bovine and mouse oocytes at the germinal vesicle stage during maturation culture and the involvement of chelation of Zn2+In pronuclear formation induction by Ca-EDTA.
Reproduction, 124; 235-240, 2002.

Shimatsu Y., Uchida M., Niki R. and Imai H.
Liquid storage of miniature boar semen.
Exp. Anim., 51; 143-147, 2002.

Murakami H., Fujimura T., Nomura K. and Imai H.
Factors influencing efficient production of transgenic rabbits.
Theriogenology, 57; 2237-2245, 2002.

Nishikimi A., Mukai J., Ikeda S. and Yamada M.
Nuclear translocation of a pre-mRNA splicing factor, p100prp1/zer1/prp6, in mouse 1-cell embryos.
J. Reprod. Dev., 48; 257-263, 2002.

Iwata H., Kimura K., Hashimoto S., Ohta M., Tominaga T. and Minami N.
Role of G6PD activity on sex ration and developmental competence of bovine embryos under oxidative stress.
J. Reprod. Dev., 48; 447-453, 2002.

Reviews & Books

Imai H.
Reprogramming of somatic nuclei and production of clone animals.
Gene, 65; 31-35, Shokabo, Tokyo, 2002.

黒坂哲・今井裕
核移植における細胞周期制御と核のリプログラミング
蛋白質 核酸 酵素、Vol.47、No.13、1804-1809、2002

武田久美子、長谷川清寿、市野清博、今井 昭、金山佳奈子、高橋清也、赤木悟史、今井 裕、山中真理子、大西 彰、花田博文
ウシ核移植産子のミトコンドリアDNA型・ヘテロプラスミーの要因
日本胚移植学雑誌 24、13-18、2002

今井 裕
体細胞のリプログラミングとクローン動物生産
遺伝、56巻、1号、31-35、2002

今井 裕
ドリーがのこした謎と新たな展開
「第二の創造」I. ウイルマット, K. キャンベル, C. タッジ著, 牧野俊一訳, pp. 409-413, 岩波書店, 2002.


2001年
Original papers

Minami N., Sasaki K., Aizawa A., Miyamoto M. and Imai H.
Analysis of gene expression in mouse 2-cell embryos using fluorescein differential display: Comparison of culture environments.
Biol. Reprod., 64; 30-35, 2001.

Azuma T., Ikeda S., Kondo T., Imai H. and Yamada M.
Ethylenediamine-N,N,N',N'- Tetraacetic acid induces parthenogenetic activation of porcine oocytes at the germinal vesicle stage, leading to formation of blastocysts.
Biol. Reprod., 64; 647-653, 2001.

Ohashi A., Minami N. and Imai H.
Nuclear accumulation of cyclin B1 in mouse 2-cell embryos is controlled by the activation of Cdc2.
Biol. Reprod., 65; 1195-1200, 2001.

Nishikimi A., Matsukawa T., Hoshino K., Ikeda S., Kira Y., Sato E. F., Inoue M. and Yamada M.
Localization of nitric oxide synthase activity in mouse unfertilized oocytes and fertilized embryos during preimplantation development.
Reproduction, 122; 957-963, 2001.

Minami N. and Imai H.
E-cadherin localization in mouse embryos cultured in an oviductal environment.
J. Mamm. Ova Res., 18; 14-19, 2001.

Uchida M., Shimatsu Y., Onoe K., Matsuyama N., Gondo Y., Niki R., Ikeda J-E. and Imai H.
Production of transgenic miniature pigs by pronuclear microinjection.
Transgenic Res., 10; 577-582, 2001.

Reviews & Books

Minami N.
Gene expression and developmental competence of mouse 2-cell embryos cultured in vitro.
In "Reproductive Biotechnology and Relating Physiology", (Miyamoto, H. and Manabe, N. eds.), Hokuto Shobo, Kyoto, pp. 155-160, 2001.

Hashimoto S. and Minami N.
In vitro maturation of bovine oocytes under low oxygen tension.
In "Reproductive Biotechnology and Relating Physiology", (Miyamoto, H. and Manabe, N. eds.), Hokuto Shobo, Kyoto, pp. 229-233, 2001.

Kurosaka S., Minami N. and Imai H.
Cytoplasmic environment and cell cycle co-ordination of recipient and donor cells in nuclear transfer embryos.
In "Reproductive Biotechnology and Relating Physiology", (Miyamoto, H. and Manabe, N. eds.), Hokuto Shobo, Kyoto, pp. 267-271, 2001.

Takeda K., Takahashi S., Akagi S., Goto Y., Kaneyama K., Kojima T., Onishi A., Hanada H. and Imai H.
Segregation of mitochondrial DNA in the heteroplasmic state in reconstructed embryos and offspring.
In "Reproductive Biotechnology and Relating Physiology", (Miyamoto, H. and Manabe, N. eds.), Hokuto Shobo, Kyoto, pp. 273-278, 2001.

Ohashi A. and Minami N.
Nuclear accumulation of cyclin B1 in mouse 2-cell embryos: Involvement of the activation of Cdc2.
In "Reproductive Biotechnology and Relating Physiology", (Miyamoto, H. and Manabe, N. eds.), Hokuto Shobo, Kyoto, pp. 297-301, 2001.

Imai H.
Recent progress of animal biotechnology in Japan.
Proceedings of Sino-Japanese Symposium on China Western Region Development, pp. 115-119, 2001.

今井 裕
生命操作における科学
科学, 71(11);1456-1457, 岩波書店, 2001.

長尾恭光
胎生期の発生分化とミトコンドリア
新ミトコンドリア学 3・12共立出版, 井上正康, 内海耕造 監修, pp. 195-201, 2001.